Nootkatone a New Active Ingredient Potential Repellent Now Registered by EPA

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From the Environmental Protection Agency:

“A new active ingredient, discovered and developed by the Centers for Disease Control and Prevention (CDC), has been registered by the Environmental Protection Agency (EPA) for use in insecticides and insect repellent ... the new ingredient, nootkatone, they may repel and kill ticks, mosquitoes, and a wide variety of other biting pests. Nootkatone is responsible for the characteristic smell and taste of grapefruit and is widely used in the fragrance industry to make perfumes and colognes. It is found in minute quantities in Alaska yellow cedar trees and grapefruit skin ... Nootkatone can now be used to develop new insect repellents and insecticides for protecting people and pets. CDC’s licensed partner, Evolva, is in advanced discussions with leading pest control companies for possible commercial partnerships ... products could be commercially available as early as 2022.”

EPA Press Release: https://www.epa.gov/pesticides/nootkatone-now-registered-epa (this page has been archived)

CDC Press Release: https://www.cdc.gov/media/releases/2020/p0810-nootkatone-registered-epa.html

Evolva Press Release: https://evolva.com/press-releases/evolva-receives-us-epa-registration-for-nootkatone-a-next-generation-protection-against-vector-borne-diseases-spread-by-insects and https://nootkashield.com/2020/08/evolva-receives-us-epa-registration-for-nootkatone/ and https://nootkashield.com/2020/08/citrus-flavoring-is-weaponized-against-insect-borne-diseases/

Further information regarding this new repellent active ingredient is below.

CDC on Nootkatone:

https://www.cdc.gov/os/technology/techtransfer/successstories/nootkatone.htm

Other Honorable Mentions of Nootkatone:

https://federallabs.org/successes/success-stories/formulation-of-nootkatone-as-repellent-and-pesticide-products-against

https://www.npr.org/2011/04/18/135468567/repelling-bugs-with-the-essence-of-grapefruit

https://search.proquest.com/openview/97e6624cecab6c1efb69041670bab056/1?pq-origsite=gscholar&cbl=2029999

https://cen.acs.org/articles/94/i14/Nootkatone-tested-mosquito-repellent.html#:~:text=CDC%20researchers%20have%20shown%20that,those%20of%20synthetic%20pesticides%20(J.

Studies on Nootkatone (and attached):